5-Fluoro-6-methyl-2-pyridinecarboxylic acid

5-Fluoro-6-methyl-2-pyridinecarboxylic acid - Names and Identifiers

Name	5-Fluoro-6-methyl-2-pyridinecarboxylic acid
Synonyms	5-Fluoro-6-methylpicolinic acid 5-fluoro-6-methylpicolinic acid 5-Fluoro-6-methylpyridine-2-carboxylicacid 5-Fluoro-6-methyl-2-pyridinecarboxylic acid 5-FLUORO-6-METHYLPYRIDINE-2-CARBOXYLIC ACID 2-Pyridinecarboxylic acid, 5-fluoro-6-methyl-
CAS	1005474-88-3
InChI	InChI=1S/C7H6FNO2/c1-4-5(8)2-3-6(9-4)7(10)11/h2-3H,1H3,(H,10,11)

5-Fluoro-6-methyl-2-pyridinecarboxylic acid - Physico-chemical Properties

Molecular Formula	C7H6FNO2
Molar Mass	155.13
Density	1.341±0.06 g/cm3(Predicted)
Boling Point	268.8±35.0 °C(Predicted)
pKa	3.65±0.10(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

5-Fluoro-6-methyl-2-pyridinecarboxylic acid - Introduction

5-Fluoro-6-methylpyridine-2-carboxylic acid is an organic compound with the formula C8H6FNO2. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: 5-fluoro-6-methylpyridine-2-carboxylic acid is a colorless or light yellow crystalline solid.
-Melting point: about 140 to 145 degrees Celsius.
-Solubility: It is soluble in water, alcohol and ether and other organic solvents.

Use:
-Chemical Intermediates: 5-Fluoro-6-methylpyridine-2-carboxylic acid is commonly used as an intermediate for the synthesis of other compounds, such as pharmaceuticals, surfactants, dyes and preservatives.
-High-efficiency pesticide: It is also widely used in the agricultural field as a raw material for high-efficiency pesticides.

Preparation Method:
As for the preparation of 5-fluorine -6-methyl pyridine -2-carboxylic acid, the specific preparation method is varied, generally including the following steps:
1. Preparation of 5-fluoro-6-methylpyridine by selective fluorination reaction.
2.5-fluorine -6-methyl pyridine is esterified with appropriate carboxylic acid anhydride to obtain 5-fluorine -6-methyl pyridine -2-carboxylic acid.

Safety Information:
-5-fluoro-6-methylpyridine-2-carboxylic acid is considered to be relatively safe under general operating conditions. However, direct contact with skin and eyes should be avoided if not necessary.
-Wear personal protective equipment such as chemical protective gloves, goggles and protective clothing when using.
-It should be stored in a dry, well-ventilated place, away from fire and oxidizing agents.
-When handling this compound, it is important to follow correct safety practices and strictly follow the relevant safety guidelines.

Last Update：2024-04-10 22:29:15